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Are You Clinically Depressed or Just Moody? Depression can range from serious to mild, temporary episodes of sadness and severe, unrelenting depression. Clinical depression is the most severe type of depression and it is also known as major depression or major depressive disorder. Clinical depression is not the same thing as being depressed over the death of a loved one, or a medical issue or thyroid disorder, it’s much deeper and more profound than most realize. How is Clinical Depression Diagnosed? To properly diagnose clinical depression, many physicians will refer to the symptom criteria for major depressive disorder in the Diagnostic and Statistical Manual of Mental Disorders, which is published by the American Psychiatric Association. The signs and symptoms of clinical depression can...